Evening Primrose
Generally Safe

Evening Primrose

Oenothera biennis
Evening PrimroseEvening StarSun Drop

Important Disclaimer

This is not medical advice. Consult a qualified healthcare provider before using any remedy, especially if pregnant, breastfeeding, on medication, or managing a health condition.

Overview

Evening primrose is a biennial wildflower native to North America, producing large yellow flowers that open in the evening. Its seed oil is one of the richest plant sources of gamma-linolenic acid (GLA), an omega-6 fatty acid that plays a crucial role in reducing inflammation and supporting hormonal balance. Evening primrose oil (EPO) is widely used for PMS, menopausal symptoms, eczema, and rheumatoid arthritis. The entire plant was used as food and medicine by Native American tribes.

Traditional Use

Evening primrose was a staple food and medicine for many Native American tribes. The Cherokee used the root as a bruise remedy and the leaves as food. The Ojibwe used the whole plant as a food source. European settlers learned of its uses from Native Americans and brought it to Europe in the 17th century, where it became known as "King's cure-all." Modern interest in evening primrose oil began in the 1970s when researchers identified its high GLA content and began investigating its therapeutic potential for inflammatory and hormonal conditions.

Key Active Compounds

Gamma-Linolenic Acid (GLA)

An omega-6 fatty acid that the body converts to anti-inflammatory prostaglandins (PGE1). GLA is essential for hormonal balance, skin health, and reducing inflammation. Evening primrose oil contains 8-10% GLA.

Linoleic Acid (LA)

The most abundant fatty acid in EPO (65-80%), an essential omega-6 that supports skin barrier function and overall cellular health.

Polyphenols

Antioxidant compounds in the leaves and flowers that provide anti-inflammatory and free radical-scavenging activity.

Evidence-Based Benefits

PMS and hormonal balance

Moderate evidence

GLA in evening primrose oil helps regulate prostaglandin balance, reducing PMS symptoms including breast tenderness, mood changes, and cramping. Multiple studies support its use for premenstrual syndrome.

Menopausal symptom relief

Some studies

Clinical studies show EPO may reduce hot flash frequency and severity in menopausal women, though results are mixed.

Eczema and skin health

Moderate evidence

GLA supports skin barrier function and reduces inflammation. Studies show EPO supplementation improves eczema symptoms, skin hydration, and overall skin health.

Rheumatoid arthritis support

Some studies

Anti-inflammatory GLA may reduce joint pain and morning stiffness in rheumatoid arthritis. Some clinical trials show modest benefits.

Common Preparation Methods

Evening Primrose Oil Capsules

Take standardized EPO capsules containing 8-10% GLA. Standard dose is 2-8 grams daily with food.

Dosage: 2-8 grams daily (500mg-1g capsules)

Take with food to improve absorption. Allow 4-8 weeks for full effects.

Topical Oil Application

Apply evening primrose oil directly to affected skin areas (eczema, dry skin, scars) twice daily. Can be mixed with other carrier oils.

Dosage: Apply 2 times daily

Excellent for dry, inflamed, or aging skin.

Leaf Tea

Steep 1-2 teaspoons of dried evening primrose leaves in 8 oz hot water for 10 minutes. Strain and drink.

Dosage: 1-2 cups daily

Traditional use; milder effect than the oil.

Safety & Cautions

Please read carefully before use

Contraindications

  • Seizure disorders: GLA may lower seizure threshold
  • Bleeding disorders: may increase bleeding risk
  • Pregnancy: avoid (may stimulate labor)
  • Schizophrenia: may worsen symptoms

Drug Interactions

  • Anticoagulants: may increase bleeding risk
  • Anticonvulsants: may reduce effectiveness
  • Phenothiazines (antipsychotics): may increase seizure risk

Possible Side Effects

  • Mild digestive upset (nausea, loose stools)
  • Headache in some individuals
  • Rare allergic reactions

Special Populations

  • Pregnancy: avoid (may stimulate uterine contractions)
  • Seizure disorders: avoid
  • Children: consult pediatrician before use

Sources & References

Quick Reference

Family / Type:

Onagraceae

Parts Used:

Seed oil, Seeds, Leaves, Root

Taste / Profile:

Oil: mild, slightly nutty; Leaves: mild, slightly bitter

Safety First

Always consult with a qualified healthcare provider before starting any new remedy, especially if you have existing health conditions or take medications.